Read of the following leaflet and mark the letter A, B, C or D on your answer sheet to indicate the option that best fits each of the numbered blanks from 7 to 12.
CASGEVY—A NEW HOPE FOR SICKLE CELL DISEASE
Revolutionary Gene-Editing Therapy Now Available on the NHS
Great news for patients with severe sickle cell disease!
⮚ On 31 January 2025, NICE approved Casgevy (exagamglogene autotemcel), a (7)_________ treatment for eligible NHS patients aged 12 and over.
❖ How Does It Work?
⮚ This innovative treatment uses CRISPR gene-editing technology to transform your own stem cells. (8)_________ process involves collecting your cells, editing them in a laboratory, and infusing them back into your body. (9)_________ the cells are your own, there is absolutely no risk of rejection by your immune system.
❖ Who Is Eligible?
⮚ Casgevy is suitable for patients who need a stem-cell transplant but cannot find a matched (10)_________. Many current treatments only control symptoms and often cause (11)_________ side effects for patients.
❖ Why This Matters
⮚ For thousands of SCD patients, this therapy could be the light at the end (12)_________ the tunnel after years of suffering. SCD disproportionately affects people from African, Caribbean, Middle Eastern, and South Asian backgrounds—making this approval a significant step toward reducing health inequalities.
❖ Take Action Today
Contact your GP or specialist to discuss whether Casgevy is right for you.
✔ Learn more: www.nhs.uk/casgevy-information
✔ Find your nearest treatment centre: www.nhs.uk/scd-centres
This therapy is offered via a managed access scheme. Eligibility criteria apply.
Together, we can fight sickle cell disease!
https://www.nice.org.uk/z
Question 7:A. gene therapy groundbreaking
B. groundbreaking gene therapy
C. groundbreaking therapy gene
D. therapy groundbreaking gene
